Synthesis of a Variety of 4,5-Functionalized Imidazol-2-Ylidenes from a Single 4,5-Unsubstituted Imidazol-2-Ylidene. J. Am. Chem. Soc. 2010, 132, 7264-7265.
Mendoza Espinosa, Daniel
2010
Mendoza-Espinosa, D.; Donnadieu, B.; Bertrand, G. Synthesis of a Variety of 4,5-Functionalized Imidazol-2-Ylidenes from a Single 4,5-Unsubstituted Imidazol-2-Ylidene. J. Am. Chem. Soc. 2010, 132, 7264-7265.
Abstract
Using the nucleophilicity of NHCs and aNHCs, as well as the leaving group ability of the former, the carbon?carbon double bond of imidazol-2-ylidenes can be readily mono- and difunctionalized. These results provide also a new light on the formation of abnormal carbene adducts from classical unsaturated NHCs.
Artículos relacionados
13C NMR and crystallographic evidence of push-pull effects in furoindolic ?-enamino esters
Total Syntheses of Five Indole Alkaloids from the Marine Bryozoan Flustra foliacea
First Total Synthesis of ()-Flustraminol B
Synthesis of Acetamido(indol-3-yl)propanol Derivatives
Synthesis of Bromoindole Alkaloids from Laurencia brongniartii
Aromatic Bromination versus Oxidation of Indolylmalonates by Bromine