Synthesis of a Variety of 4,5-Functionalized Imidazol-2-Ylidenes from a Single 4,5-Unsubstituted Imidazol-2-Ylidene. J. Am. Chem. Soc. 2010, 132, 7264-7265.
Mendoza Espinosa, Daniel
2010
Mendoza-Espinosa, D.; Donnadieu, B.; Bertrand, G. Synthesis of a Variety of 4,5-Functionalized Imidazol-2-Ylidenes from a Single 4,5-Unsubstituted Imidazol-2-Ylidene. J. Am. Chem. Soc. 2010, 132, 7264-7265.
Abstract
Using the nucleophilicity of NHCs and aNHCs, as well as the leaving group ability of the former, the carbon?carbon double bond of imidazol-2-ylidenes can be readily mono- and difunctionalized. These results provide also a new light on the formation of abnormal carbene adducts from classical unsaturated NHCs.
Artículos relacionados
Stereochemical assignment of naturally occurring 2,3-epoxy-2-methylbutanoate esters
Synthesis of Bromoindole Alkaloids from Laurencia brongniartii
Transesterifications mediated by t-BuNH2
Aromatic Bromination versus Oxidation of Indolylmalonates by Bromine
Absolute configuration determination of 2-(2-oxo-3-indolyl)acetamide derivatives
Synthesis of Acetamido(indol-3-yl)propanol Derivatives
13C NMR and crystallographic evidence of push-pull effects in furoindolic ?-enamino esters
Synthesis of Indolylindolines Mediated by tert-BuNH2
Total Syntheses of Five Indole Alkaloids from the Marine Bryozoan Flustra foliacea