2012
Morales-Rios, MS; Rivera-Becerril, E; Lopez-Camacho, PY ; Perez-Rojas, NA ; Suarez-Castillo, OR, Preparation of O-Methyl Substituted 2-Oxofuro- and 2-Oxopyrrolidinoindolines by Reductive Lactonization of Oxindol-3-ylacetic Acids, NATURAL PRODUCT COMMUNICATIONS. Año: 2012 Volume: 7 Issue: 11 Pages: 1445-1451.ISSN: 1934-578X
Abstract
A practical procedure for the preparation of O-methyl substituted 3a,8-dialkyl-2-oxofuroindolines is described. Reductive lactonization of the corresponding oxindol-3-ylacetic acids provides a route for the formation of this class of compounds. Further transformation of 2-oxofuroindolines into 2-oxopyrrolidinoindolines, and then to pyrrolidinoindolines demonstrates their versatility as key intermediates in natural products synthesis. The results of single-crystal X-ray crystallographic analyses are given for five of the studied compounds.
The absoluteconfiguration of cuauhtemone and related compounds
Synthesis of Bromoindole Alkaloids from Laurencia brongniartii
Trapping enols of esters and lactones with diazomethane
Configuration, stereodynamics and crystal structure of 3-substituted-2-oxofuro[2,3-b]indoles
Role of lipid peroxidation in biliary obstruction in the rat
Synthesis of Acetamido(indol-3-yl)propanol Derivatives
Synthesis of 6-bromo-2-arylindoles using 2-iodobenzoic acid as precursor
Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2