Producción Científica Profesorado

Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2



Suárez Castillo, Oscar Rodolfo

2007

Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2. Oscar R. Suárez-Castillo, Luis Alberto Montiel-Ortega, Myriam Meléndez-Rodríguez, Maricruz Sánchez-Zavala. DOI: http://dx.doi.org/10.1016/j.tetlet.2006.11.024


Abstract


An efficient, simple protocol for the selective cleavage of a variety of N-alkoxycarbonyl protecting groups by t-BuNH2/MeOH is described. The scope of the procedure was explored for a series of indole, aniline and pyrrolidine carbamate derivatives containing other potentially reactive functional groups affording a clean cleavage of the carbamate group.



Producto de Investigación




Artículos relacionados

Conformationalstudies of N-carbomethoxy-2-alkoxyindolenines by dynamic NMR, crystallography, and mol...

Total Syntheses of Five Indole Alkaloids from the Marine Bryozoan Flustra foliacea

Stereochemical assignment of naturally occurring 2,3-epoxy-2-methylbutanoate esters

Conformational studies on indole alkaloids from Flustra foliacea by NMR and molecular modeling

Aromatic Bromination versus Oxidation of Indolylmalonates by Bromine

13C NMR and crystallographic evidence of push-pull effects in furoindolic ?-enamino esters

Reactivity of TpMe2Ir(C2H4)(DMAD) with carboxylic acids. A DFT study on geometrical isomers and stru...

Configuration, stereodynamics and crystal structure of 3-substituted-2-oxofuro[2,3-b]indoles

Transesterifications mediated by t-BuNH2

Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2