Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2
Suárez Castillo, Oscar Rodolfo
2007
Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2. Oscar R. Suárez-Castillo, Luis Alberto Montiel-Ortega, Myriam Meléndez-Rodríguez, Maricruz Sánchez-Zavala. DOI: http://dx.doi.org/10.1016/j.tetlet.2006.11.024
Abstract
An efficient, simple protocol for the selective cleavage of a variety of N-alkoxycarbonyl protecting groups by t-BuNH2/MeOH is described. The scope of the procedure was explored for a series of indole, aniline and pyrrolidine carbamate derivatives containing other potentially reactive functional groups affording a clean cleavage of the carbamate group.
Artículos relacionados
First Total Synthesis of ()-Flustraminol B
Synthesis of Bromoindole Alkaloids from Laurencia brongniartii
Trapping enols of esters and lactones with diazomethane
Conformational studies on indole alkaloids from Flustra foliacea by NMR and molecular modeling
Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2
The absoluteconfiguration of cuauhtemone and related compounds
Regioselective Synthesis of 3-Indolyl(alkoxy)acetates
Synthesis of Acetamido(indol-3-yl)propanol Derivatives
13C NMR and crystallographic evidence of push-pull effects in furoindolic ?-enamino esters
Stereochemical assignment of naturally occurring 2,3-epoxy-2-methylbutanoate esters