Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2
Suárez Castillo, Oscar Rodolfo
2007
Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2. Oscar R. Suárez-Castillo, Luis Alberto Montiel-Ortega, Myriam Meléndez-Rodríguez, Maricruz Sánchez-Zavala. DOI: http://dx.doi.org/10.1016/j.tetlet.2006.11.024
Abstract
An efficient, simple protocol for the selective cleavage of a variety of N-alkoxycarbonyl protecting groups by t-BuNH2/MeOH is described. The scope of the procedure was explored for a series of indole, aniline and pyrrolidine carbamate derivatives containing other potentially reactive functional groups affording a clean cleavage of the carbamate group.
Artículos relacionados
Configuration, stereodynamics and crystal structure of 3-substituted-2-oxofuro[2,3-b]indoles
Role of lipid peroxidation in biliary obstruction in the rat
The absoluteconfiguration of cuauhtemone and related compounds
Total Syntheses of Five Indole Alkaloids from the Marine Bryozoan Flustra foliacea
First Total Synthesis of ()-Flustraminol B
Synthesis of Indolylindolines Mediated by tert-BuNH2
Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2
Unimolecular rearrangements of ketene-O,O-acetals and fragmentations occurring in the gas phase
Synthesis of 6-bromo-2-arylindoles using 2-iodobenzoic acid as precursor