2006
Preparation of 3-hydroxyoxindoles with dimethyldioxirane and their use for the synthesis of natural products. Oscar R. Suárez-Castillo, Maricruz Sánchez-Zavala, Myriam Meléndez-Rodríguez, Luis E. Castelán-Duarte, Martha S. Morales-Ríos, Pedro Joseph-Natha. http://dx.doi.org/10.1016/j.tet.2006.01.036
Abstract
This work describes a general protocol for the oxidation of indole and oxindole derivatives with dimethyldioxirane to give 3-hydroxyoxindoles present in many natural products. This strategy allowed us to synthesize the natural product 1, to carry out the first total synthesis of 4, a formal total synthesis of donaxaridine (5) and to achieve the synthesis of pyrroloindoline 8, a debromo analogue of the natural product flustraminol B (7).
One-potsynthesis of conformationallyrestrictedspirooxindoles
Stereochemical assignment of naturally occurring 2,3-epoxy-2-methylbutanoate esters
Synthesis of 6-bromo-2-arylindoles using 2-iodobenzoic acid as precursor
The absoluteconfiguration of cuauhtemone and related compounds
Total Syntheses of Five Indole Alkaloids from the Marine Bryozoan Flustra foliacea
Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2
First Total Synthesis of ()-Flustraminol B
Aromatic Bromination versus Oxidation of Indolylmalonates by Bromine