Facile synthesis of 1,3,6-oxadiazepines from 2,2?-(1,2-ethanediyldiimino)bisphenols
Rojas Lima, Susana
2001
Ma. Eugenia Ochoa Becerra, Susana Rojas-Lima, Herbert Höpfl, Patricia Rodríguez, Dolores Castillo, Rosa Luisa Santillán Baca and José Norberto Farfán García. "Facile synthesis of 1,3,6-oxadiazepines from 2,2'-(1,2-ethanediyldiimino)bisfenols. Tetrahedron, 57, 55-64 (2001). DOI: http://dx.doi.org/10.1016/S0040-4020(00)00984-4
Abstract
A useful sequence of reactions for the syntheses of a variety of heterocyclic systems including an oxadiazepine ring is described. The key step involves the condensation of substituted 2,2?-(1,2-ethanediyldiimino)bisphenols with ethanedial to provide stereoselectively the 6a,7a-trans-6,6a,7a,8,15,16-hexahydro[1,4]benzoxazine[4?,3?:6,7][1,3,6]oxadiazepino[2,3-c][1,4]-benzoxazine-6,8-diol framework, as established by X-ray diffraction analyses.
Artículos relacionados
Preparation of N-aryl-substituted spiro-?-lactams via Staudinger cycloaddition
Study of the reactivity of squarylferrocenes. Addition of amines and aminoesters
Furocoumarins of three species of the genus Dorstenia
Stereoselective addition of allylmagnesium chloride to the CN bond of [4.3.0] boron heterobicycles
Diastereoselective Synthesis of Spiro-?-lactams via Staudinger Reaction
Aroylthioureas: new organic ionophores for heavy-metal ion selective electrodes