Phenylboronic acid catalyzed-cyanide promoted, one-pot synthesis of 2-(2-hydroxyphenyl)benzoxazole derivatives
Rojas Lima, Susana
2011
Heraclio López-Ruiz, Horacio Briseño-Ortega, Susana Rojas-Lima, Rosa Santilllán, Norberto Farfán. Phenylboronic acid catalyzed-cyanide promoted, one-pot synthesis of 2-(2-hydroxyphenyl)benzoxazole derivatives . Tetrahedron Letters 2011, 52, 4308-4312. DOI: http://dx.doi.org/10.1016/j.tetlet.2011.06.039
Abstract
A novel, one-pot, phenylboronic acid catalyzed, cyanide promoted synthesis of 2-(2-hydroxyphenyl)benzoxazoles from salicylaldehydes and o-aminophenols is described. The synthesis is characterized by mild conditions, short reaction times, and simple workup of crystalline, high purity products.
Artículos relacionados
Diastereoselective alkylation of chiral glycinate derivatives containing the ?-phenylethyl group.
Et3, and efficient Mediator for Xanthate Transfer Based Radical Processes.