Diastereoselective alkylation of chiral glycinate derivatives containing the ?-phenylethyl group.
Rojas Lima, Susana
2011
Rodríguez-Garnica Cristina, López-Ruiz Heraclio,* Rojas-Lima Susana, Álvarez - Hernández Alejandro, Tapia-Benavides Rafael, García-López María Concepción. Diastereoselective alkylation of chiral glycinate derivatives containing the ?-phenylethyl group. Journal of the Mexican Chemical Society, 55(3), 148-153. (2011)
Abstract
Novel chiral glycinate derivatives (S)-6 and (S)-7 containing the a-phenylethyl group, were prepared and studied as potentialprecursors of enantiopure a-substituted-a-amino acids. In particular, the alkylation of enolate (S)-7-Li showed substantial (78:22 dr)stereoinduction by the N-(1-phenylethyl)benzamide chiral auxiliary.Addition of DMPU showed no appreciable effect upon the diastereoselectivity
Artículos relacionados
Synthesis and Structures of some Lithium and Sodium (Aminoalcoholato)hydrido Aluminates
Study of the reactivity of squarylferrocenes. Addition of amines and aminoesters
Ylidaddukte der Penteltrichloride
X-ray crystallographic study of neutral boron chelates with ?-diketones and tropolone
Furocoumarins of three species of the genus Dorstenia
Structural studies of spiroarsoranes derived from 2-aminophenols