Producción Científica Profesorado

Diastereoselective alkylation of chiral glycinate derivatives containing the ?-phenylethyl group.



Rojas Lima, Susana

2011

Rodríguez-Garnica Cristina, López-Ruiz Heraclio,* Rojas-Lima Susana, Álvarez - Hernández Alejandro, Tapia-Benavides Rafael, García-López María Concepción. Diastereoselective alkylation of chiral glycinate derivatives containing the ?-phenylethyl group. Journal of the Mexican Chemical Society, 55(3), 148-153. (2011)


Abstract


Novel chiral glycinate derivatives (S)-6 and (S)-7 containing the a-phenylethyl group, were prepared and studied as potentialprecursors of enantiopure a-substituted-a-amino acids. In particular, the alkylation of enolate (S)-7-Li showed substantial (78:22 dr)stereoinduction by the N-(1-phenylethyl)benzamide chiral auxiliary.Addition of DMPU showed no appreciable effect upon the diastereoselectivity



Producto de Investigación




Artículos relacionados

Further insight into three center hydrogen bonding. Participation in tautomeric equilibria of hetero...

Cathepsins X and B Can Be Differentiated through Their Respective Mono- and Dipeptidyl Carboxypeptid...

Preparation of Seven- and Eight-Membered Boron Heterocycles from Different Salen Ligands and Arylbor...

Synthesis and Study of Isomeric Benzo[1,4]oxazines and Benzothiazolines by NMR Spectroscopy and X-Ra...

Et3, and efficient Mediator for Xanthate Transfer Based Radical Processes.

Phenylmethyl 2,3,4-tri-O-acetyl--D-fucopyranoside

Ylidaddukte der Penteltrichloride

Diastereoselective alkylation of chiral glycinate derivatives containing the ?-phenylethyl group.

Diastereoselective Synthesis of Spiro-?-lactams via Staudinger Reaction

Facile synthesis of 1,3,6-oxadiazepines from 2,2?-(1,2-ethanediyldiimino)bisphenols